A search for new physics is performed using events with isolated same-sign leptons and jets in the final state. Results are based on the full sample of proton-proton collisions collected from the Large Hadron Collider at a center-of-mass energy of 8 TeV with the CMS detector and corresponding to an integrated luminosity of 19.5 fb⁻¹. No excess above the standard model background is observed and constraints on a number of new physics models are set