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Article
Peer Reviewed

Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells

Krogan, Nevan;
Tosti, E;
Katakowski, JA;
Schaetzlein, S;
Kim, HS;
Ryan, CJ;
Shales, M;
Roguev, A;
Krogan, NJ;
Palliser, D;
Keogh, MC

UC San Francisco Previously Published Works (2014)

© 2014 Tosti et al.; licensee BioMed Central Ltd.Background: The evolutionarily conserved DNA mismatch repair (MMR) system corrects base-substitution and insertion-deletion mutations generated during erroneous replication. The mutation or inactivation of m