- Imbert, Elizabeth;
- Kinley, Patrick M;
- Scarborough, Ashley;
- Cawley, Caroline;
- Sankaran, Madeline;
- Cox, Sarah N;
- Kushel, Margot;
- Stoltey, Juliet;
- Cohen, Stephanie;
- Fuchs, Jonathan D
We report the public health response to a coronavirus disease 2019 (COVID-19) outbreak in a San Francisco shelter where 67% of residents and 17% of staff tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe the limited utility of case investigation, person-based contact tracing and symptom screening, and the benefits of mass testing in outbreak response.