- Broaddus, V Courtney;
- Barbone, D;
- Cheung, P;
- Battula, S;
- Busacca, S;
- Gray, SG;
- Longley, DB;
- Bueno, R;
- Sugarbaker, DJ;
- Fennell, DA;
- Broaddus, VC
When grown in 3D cultures as spheroids, mesothelioma cells acquire a multicellular resistance to apoptosis that resembles that of solid tumors. We have previously found that resistance to the proteasome inhibitor bortezomib in 3D can be explained by a lack