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Scholarly Works (2 results)

Article
Peer Reviewed

Regulatory network decoded from epigenomes of surface ectoderm-derived cell types

Bastian, Boris;
Costello, Joseph;
Lowdon, RF;
Zhang, B;
Bilenky, M;
Mauro, T;
Li, D;
Gascard, P;
Sigaroudinia, M;
Farnham, PJ;
Bastian, BC;
Tlsty, TD

UC San Francisco Previously Published Works (2014)

© 2014 Macmillan Publishers Limited. All rights reserved.Developmental history shapes the epigenome and biological function of differentiated cells. Epigenomic patterns have been broadly attributed to the three embryonic germ layers. Here we investigate ho

Article
Peer Reviewed

DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

Costello, Joseph;
Tlsty, Thea;
Weiss, Arthur;
Xie, M;
Hong, C;
Zhang, B;
Lowdon, RF;
Xing, X;
Li, D;
Zhou, X;
Lee, HJ;
Maire, CL;
Ligon, KL

UC San Francisco Previously Published Works (2013)

Transposable element (TE)-derived sequences comprise half of the human genome and DNA methylome and are presumed to be densely methylated and inactive. Examination of genome-wide DNA methylation status within 928 TE subfamilies in human embryonic and adult