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Scholarly Works (2 results)

Article
Peer Reviewed

Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis

Maher, Jacquelyn;
Pierce, AA;
Pickens, MK;
Siao, K;
Grenert, JP;
Maher, JJ

UC San Francisco Previously Published Works (2015)

© 2015 Pierce et al. Background: Saturated fatty acids are toxic to liver cells and are believed to play a central role in the pathogenesis of non-alcoholic steatohepatitis. In experimental steatohepatitis induced by feeding mice a methionine-choline-defic

Article
Peer Reviewed

Impact of insulin resistance on HCV treatment response and impact of HCV treatment on insulin sensitivity using direct measurements of insulin action

Maher, Jacquelyn;
Khalili, Mandana;
Bacchetti, Peter;
Brandman, D;
Ayala, CE;
Maher, JJ

UC San Francisco Previously Published Works (2012)

OBJECTIVE - Insulin resistance, as measured by surrogate markers, is associated with lower response to hepatitis C virus (HCV) therapy and may improve with HCV eradication. We prospectively evaluated the impact of directly measured insulin resistance and a