We have developed the "S_IX" statistic to identify bright, highly-likely
Active Galactic Nucleus (AGN) candidates solely on the basis of WISE, 2MASS and
Rosat all-sky survey data. This statistic was optimized with data from the
preliminary WISE survey and the SDSS, and tested with Lick 3-m Kast
spectroscopy. We find that sources with S_IX < 0 have a <~95% likelihood of
being an AGN (defined in this paper as a Seyfert 1, quasar or blazar). This
statistic was then applied to the full WISE/2MASS/RASS dataset, including the
final WISE data release, to yield the "W2R" sample of 4,316 sources with S_IX <
0. Only 2,209 of these sources are currently in the Veron-Cetty and Veron (VCV)
catalog of spectroscopically confirmed AGN, indicating that the W2R sample
contains nearly 2,000 new, relatively bright (J <~ 16) AGN.
We utilize the W2R sample to quantify biases and incompleteness in the VCV
catalog. We find it is highly complete for bright (J < 14), northern AGN, but
the completeness drops below 50% for fainter, southern samples and for sources
near the Galactic plane. This approach also led to the spectroscopic
identification of 10 new AGN in the Kepler field, more than doubling the number
of AGN being monitored by Kepler. This has identified ~1 bright AGN every 10
square degrees, permitting construction of AGN samples in any sufficiently
large region of sky.