- Muschen, Markus;
- Sun, H;
- Lin, DC;
- Guo, X;
- Masouleh, BK;
- Gery, S;
- Cao, Q;
- Alkan, S;
- Ikezoe, T;
- Akiba, C;
- Paquette, R
Survival of cancer cells relies on the unfolded protein response (UPR) to resist stress triggered by the accumulation of misfolded proteins within the endoplasmic reticulum (ER). The IRE1α-XBP1 pathway, a key branch of the UPR, is activated in many cancers