The aim of this thesis is to develop two improved methods for amplifying genomic DNA and to order the individual amplified templates into arrays for high throughput and cost-efficient genome sequencing. The first method focuses on the synthesis of functionalized linear polymers for fabricating arrays for DNA amplification. These arrays can be used to improve PCR amplification of single molecules by extending the reaction into three-dimensional space similar to a solution reaction while each reaction is confined within the structure of the array. A method was developed for the synthesis and purification of linear polyacrylamide copolymers that can be captured and visualized. Several conjugation methods were investigated for functionalizing the copolymers with primers. The second amplification method utilized linear rolling circle amplification to produce long continuous DNA molecules with multiple copies of the template sequence. These single molecules could be captured onto an array for sequencing. The number of amplified copies in these molecules was characterized by several methods including gel electrophoresis, digestion, probe saturation, and electric field stretching. The amplified products displayed a broad distribution in length. However, they could be captured on a surface and imaged by fluorescence microscopy, and are accessible for downstream applications. Microemulsions can be used to further control the sizes of DNA single molecule amplicons. A microfluidic device was designed and fabricated for creating uniform microemulsions. Microemulsions with a coefficient of variation around 0.15 could be produced under various conditions. Further improvement in the device will be required to make it more reproducible