Background: Image-guided endovascular interventions have gained increasing popularity in clinical practice, and magnetic resonance imaging (MRI) is emerging as an attractive alternative to Xray fluoroscopy for guiding such interventions. Steering catheters

Transgenic mouse lines are essential tools for understanding the connectivity, physiology and function of neuronal circuits, including those in the retina. This report compares transgene expression in the retina of a tyrosine hydroxylase (TH)-red fluorescent protein (RFP) mouse line with three catecholamine-related Cre recombinase mouse lines [TH-bacterial artificial chromosome (BAC)-, TH-, and dopamine transporter (DAT)-Cre] that were crossed with a ROSA26-tdTomato reporter line. Retinas were evaluated and immunostained with commonly used antibodies including those directed to TH, GABA and glycine to characterize the RFP or tdTomato fluorescent-labeled amacrine cells, and an antibody directed to RNA-binding protein with multiple splicing to identify ganglion cells. In TH-RFP retinas, types 1 and 2 dopamine (DA) amacrine cells were identified by their characteristic cellular morphology and type 1 DA cells by their expression of TH immunoreactivity. In the TH-BAC-, TH-, and DAT-tdTomato retinas, less than 1%, ∼ 6%, and 0%, respectively, of the fluorescent cells were the expected type 1 DA amacrine cells. Instead, in the TH-BAC-tdTomato retinas, fluorescently labeled AII amacrine cells were predominant, with some medium diameter ganglion cells. In TH-tdTomato retinas, fluorescence was in multiple neurochemical amacrine cell types, including four types of polyaxonal amacrine cells. In DAT-tdTomato retinas, fluorescence was in GABA immunoreactive amacrine cells, including two types of bistratified and two types of monostratified amacrine cells. Although each of the Cre lines was generated with the intent to specifically label DA cells, our findings show a cellular diversity in Cre expression in the adult retina and indicate the importance of careful characterization of transgene labeling patterns. These mouse lines with their distinctive cellular labeling patterns will be useful tools for future studies of retinal function and visual processing.

This paper presents a study of events produced in 29-GeV electron-positron annihilation in which there are just two noncollinear charged particles, no detected photons, and two or more undetected particles. These events can be explained by attributing them primarily to the reactions e+e-'e+e-e+e- and e+e-'e+e-+- where just two particles appear in the Mark II detector. There is no evidence for unconventional sources for such events. © 1986 The American Physical Society.

We use data from the Mark II experiment at PEP to search for the process B→h0X for mh0 between 50 and 210 MeV/c2. No evidence for the Higgs boson is seen in this mass range. The limit obtained rules out the standard Higgs boson for masses between 70 and 210 MeV/c2 and significantly constrains extensions of the Higgs sector. © 1989.

A precise measurement of the ratio R of the total cross section e+e-hadrons to the pointlike cross section e+e-+- at a center-of-mass energy of 29.0 GeV is presented. The data were taken with the upgraded Mark II detector at the SLAC storage ring PEP. The result is R=3.920.050.09. The luminosity has been determined with three independent luminosity monitors measuring Bhabha scattering at different angular intervals. Recent calculations of higher-order QED radiative corrections are used to estimate the systematic error due to missing higher-order radiative corrections in the Monte Carlo event generators. © 1991 The American Physical Society.

Data taken by the Mark II detector at the PEP storage ring was used to measure the rate of dilepton production in multihadronic events produced by e+e- annihilation at √s=29 GeV. We determine the probability that a hadron initially containing a b (b̄) quark decays to a positive (negative) lepton to be 0.17-0.08+0.15, with 90% confidence level limits of 0.06 and 0.38. © 1990.

Data taken by the Mark II detector at the SLAC e+e- storage ring PEP was used to search for exclusive decays of D and B mesons into two charged leptons plus a charged pion or kaon. All possible charge and lepton combinations consistent with charge conservation were considered and no evidence for any signals was found. We obtain upper limits for the various branching ratios ranging from 2.5×10-3 to 9.2×10-3, at a 90% confidence level. Some of these limits can be used to constrain leptoquark masses in various models. © 1990 The American Physical Society.

Production rates of multijet hadronic final states are studied in e+e- annihilation at 29 GeV center of mass energy. QCD shower model calculations with exact first order matrix element weighting at the first gluon vertex are capable of reproducing the observed multijet event rates over a large range of jet pair masses. The method used to reconstruct jets is well suited for directly comparing experimental jet rates with parton rates calculated in perturbative QCD. Evidence for the energy dependene of αs is obtained by comparing the observed production rates of 3-jet events with results of similar studies performed at higher center of mass energies. © 1989 Springer-Verlag.

We have searched for the annihilation of e+e- into the exclusive channels e and at s =29 GeV, using 226 and 133 pb-1, respectively, of data taken with the Mark II detector at the SLAC storage ring PEP. The resulting candidate sample is compatible with the expected background from pair production. Our analysis yields 95%-C.L. cross-section limits of e/<1.8×10-3 and /<6.1×10-3, where is the QED cross section for production of a lepton pair. This is the first high-Q2 test of lepton-flavor conservation involving leptons. © 1991 The American Physical Society.