Search

Scholarly Works (3 results)

Sort By:

Article
Peer Reviewed

Structure of the human autophagy initiating kinase ULK1 in complex with potent inhibitors

Shokat, Kevan;
Lazarus, MB;
Novotny, CJ;
Shokat, KM

UC San Francisco Previously Published Works (2015)

© 2014 American Chemical Society.Autophagy is a conserved cellular process that involves the degradation of cellular components for energy maintenance and cytoplasmic quality control that has recently gained interest as a novel target for a variety of huma

Article
Peer Reviewed

Overcoming resistance to HER2 inhibitors through state-specific kinase binding

Shokat, Kevan;
Novotny, CJ;
Pollari, S;
Park, JH;
Lemmon, MA;
Shen, W;
Shokat, KM

UC San Francisco Previously Published Works (2016)

Article
Peer Reviewed

Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor

Shokat, Kevan;
Rodrik-Outmezguine, VS;
Okaniwa, M;
Yao, Z;
Novotny, CJ;
McWhirter, C;
Banaji, A;
Won, H;
Wong, W;
Berger, M;
de, E

UC San Francisco Previously Published Works (2016)