Let $C$ be a smooth projective geometrically connected curve over a finite field with function field $K$ or the spectrum of the ring of integers in a number field $K$. Let $X$ be a smooth projective geometrically connected curve over $K$. Let $\pi:\mathcal{X}\longrightarrow C$ be a proper regular model of $X/K$. Artin and Grothendieck proved that there is an isomorphism $Sha(\Pic^{0}_{X/K})\cong \mathrm{Br}(\mathcal{X})$ up to finite groups. As a result, this implies that the BSD conjecture for $\Pic^{0}_{X/K}$ is equivalent to the Tate conjecture for the surface $\mathcal{X}$ when $K$ is in positive characteristic. In this thesis, we generalize this result to fibrations $\pi:\mathcal{X}\longrightarrow C$ of arbitraryrelative dimensions fibered over $C$, where $C$ is a smooth projective curve over arbitrary finitely generated fields or the spectrum of the ring of integers in a number field. As a consequence, we reprove the reduction theorem of the Tate conjecture for divisors due to Andr