- Van 'T Veer, Laura;
- Ashworth, Alan;
- Daemen, A;
- Wolf, DM;
- Korkola, JE;
- Griffith, OL;
- Frankum, JR;
- Brough, R;
- Jakkula, LR;
- Wang, NJ;
- Natrajan, R;
- Reis-Filho, JS
Poly(ADP-ribose) polymerase (PARP) is an enzyme involved in DNA repair. PARP inhibitors can act as chemosensitizers, or operate on the principle of synthetic lethality when used as single agent. Clinical trials have shown drugs in this class to be promisin