Search

Scholarly Works (1 results)

Article
Peer Reviewed

Does Naloxone Reinstate Secondary Hyperalgesia in Humans after Resolution of a Burn Injury? A Placebo-Controlled, Double-Blind, Randomized, Cross-Over Study

Rowbotham, Michael;
Pereira, MP;
Werner, MU;
Ringsted, TK;
Rowbotham, MC;
Taylor, BK;
Dahl, JB

UC San Francisco Previously Published Works (2013)

Introduction:Development of secondary hyperalgesia following a cutaneous injury is a centrally mediated, robust phenomenon. The pathophysiological role of endogenous opioid signalling to the development of hyperalgesia is unclear. Recent animal studies, ca