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Open Access Publications from the University of California

Scholarly Works (4714 results)

  • Article
  • Peer Reviewed
UC San Francisco Previously Published Works (2015)
    • Article
    • Peer Reviewed
    UCLA Previously Published Works (2015)
    ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) proteases comprise the most recently discovered branch of the extracellular metalloenzymes. Research during the last 15years, uncovered their association with a variety of physiological and pathological processes including blood coagulation, tissue repair, fertility, arthritis and cancer. Importantly, a frequent feature of ADAMTS enzymes relates to their effects on vascular-related phenomena, including angiogenesis. Their specific roles in vascular biology have been clarified by information on their expression profiles and substrate specificity. Through their catalytic activity, ADAMTS proteases modify rather than degrade extracellular proteins. They predominantly target proteoglycans and glycoproteins abundant in the basement membrane, therefore their broad contributions to the vasculature should not come as a surprise. Furthermore, in addition to their proteolytic functions, non-enzymatic roles for ADAMTS have also been identified expanding our understanding on the multiple activities of these enzymes in vascular-related processes.
      • Article
      • Peer Reviewed
      UC San Francisco Previously Published Works (2014)
      Introduction: Defensive medicine is a medical practice in which health care providers' primary intent is to avoid criticism and lawsuits, rather than providing for patients' medical needs. The purpose of this study was to characterize medical students' exp
        • Article
        • Peer Reviewed
        UC Berkeley Previously Published Works (2016)
        Because of scale effects, idea-based growth models imply that larger countries should be much richer than smaller ones. New trade models share the same counterfactual feature. In fact, new trade models exhibit other counterfactual implications associated with scale effects: import shares decrease and relative income levels increase too steeply with country size. We argue that these implications are largely a result of the standard assumption that countries are fully integrated domestically. We depart from this assumption by treating countries as collections of regions that face positive costs to trade among themselves. The resulting model is largely consistent with the data.
          • Article
          • Peer Reviewed
          UC San Francisco Previously Published Works (2023)
          Reproductive longevity is associated with health outcomes. Early menopause, loss of ovarian function, and male infertility are linked to shorter lifespan and increased adverse health outcomes. Here we examined the extragonadal effects of whole animal loss of spermatogenesis and oogenesis specific basic helix-loop-helix 1 (Sohlh1) gene in mice, a well-described mouse model of female and male infertility. Sohlh1 encodes a transcription factor that is primarily expressed in the male and female germline and regulates germline differentiation. The Sohlh1 knockout mouse model, just like human individuals with SOHLH1 loss of function, presents with hypergonadotropic hypogonadism and loss of ovarian function in females and impaired spermatogenesis in males, with a seemingly gonad restricted phenotype in both sexes. However, extragonadal phenotyping revealed that Sohlh1 deficiency leads to abnormal immune profiles in the blood and ovarian tissues of female animals, sex-specific alterations of metabolites, and behavior and cognition changes. Altogether, these results show that Sohlh1 deficiency impacts overall health in both male and female mice.
            Cover page: Sohlh1 loss of function male and female infertility model impacts overall health beyond gonadal dysfunction in mice†.
            • Article
            • Peer Reviewed
            UC Irvine Previously Published Works (2023)
              Cover page: Longevity Estimates of Canary Palms and Dragon Trees via Radiocarbon Dating: Initial Results
              • Article
              CSW Update Newsletter (2010)

              The author argues that commonplace sexist practices lay the conditions for femicide and the political discourses that surround it. She examines two case studies: the over five hundred femicides that have occurred in the border city of Juarez, Mexico since 1993 and George Sodini's murder of three women in a gym in a suburb of Pittsburgh, Pennsylvania.

                Cover page: From Misogyny to Murder: Everyday Sexism and Femicide in a Cross-Cultural Context
                • Article
                • Peer Reviewed
                nineteen sixty nine: an ethnic studies journal, Volume 2, Issue 1 (2013)
                  Cover page: Mutual Care Mutual Aid
                  • Article
                  • Peer Reviewed
                  UC Berkeley Previously Published Works (2015)
                  © 2016 Women & Performance Project Inc. Using the auto/biography, Vanessa del Rio: Fifty Years of Slightly Slutty Behavior as the primary text, this paper investigates how an embodied understanding of race and class alters our understanding of gendered experiences of violence and pleasure. It asks: what happens when the life experiences of an aging Afro-Latina porn star are positioned at the very heart of feminist investigations into the relationship between sexual experience and knowledge production? In the process, this paper reflects on how images and text function as complicated triggers for the attachments, identifications, desires, and traumas of our own corporeal embodiments and sexual histories.
                    Cover page: Pornographic encounters and interpretative interventions: Vanessa del Rio: Fifty Years of Slightly Slutty Behavior
                    • Article
                    UC Merced Undergraduate Research Journal, Volume 12, Issue 2 (2020)

                    In today’s world, we’ve invented many new technologies that have allowed us to map out the earth’s surface but just as we can map out surfaces in a large scale, we can also map out surfaces in a very small scale such as in nanometers. Thus, giving us opportunities to study & discover various materials such as molybdenum disulfide (MoS2) crystalline flakes. MoS2 being a material that has a similar yet different structure to graphene, low friction when compared to SiO2 (a low friction material as is), and provides many potential applications that can be implemented into aerospace as a solid lubricant. But like any fellow researcher studying a material, each has their own methods/techniques that they use to obtain results. In our proposal, we will cover the research that has taken place to provide a consensus of MoS2’s potential application as a solid lubricant in aerospace to its low frictional properties in the nanometer scale. And the technologies we’ll be looking into to access for our methods/techniques for researching will be Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), X-Ray Photoelectric Spectroscopy (XPS), X-Ray Diffraction (XRD), and Tribometers at the University of California, Merced (UC Merced).

                      Cover page: The Methods to Unlock Molybdenum DisulfideCreative Commons 'BY-NC-ND' version 4.0 license
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