Rodent pest problems and their control in Italy are reviewed. Two rats, Rattus norvegicus and Rattus rattus, and the field mouse, Apodemus sylvaticus, are often important pests both in rural and forestry areas. Other species, such as voles, Microtus arvalis and Microtus (Pitymys) savii, in orchards and in horticulture, and Sciurus vulgaris and Myoxus (Glis) glis in forestry, sometimes represent serious problems. For each species the kind of damage and control is recorded, and additional considerations are supplied to the public and private organizations responsible for rodent control.