Coronavirus Disease 2019 (COVID-19) has had an enormous impact on both the medical community as well as society as a whole. Research on the pathogenesis and the treatment of the disease is rapidly emerging, with new observations and hypotheses appearing daily. One aspect that has been receiving increasing attention is the occurrence of both arterial and venous thrombotic complications in patients with COVID-19. We report three cases of thromboembolic complications in patients affected by COVID-19 and discuss clinical features, pathophysiology, and the proposed approaches to management of vascular complications in these patients. Through our discussion, we also urge physicians to be vigilant for any symptoms or signs suggestive of thrombosis in patients with COVID-19.

Malignant pleural mesothelioma is a rare but aggressive cancer with limited treatment options. Percutaneous cryoablation is emerging as a promising treatment option for control of local recurrence and for palliative management of the disease-related symptoms. At times, recurrent malignant pleural mesothelioma is difficult to target as it can recur within the mediastinum and can be surrounded by vital organs and large vessels. This case report describes a challenging yet safe and successful transvertebral approach for percutaneous cryoablation of a paraesophageal mass for palliative treatment of a patient with single-site recurrent metastatic malignant pleural mesothelioma within the mediastinum.