Vacor (RH-787), a relatively new rodenticide, was evaluated for the control of Rattus rattus rufescens. The symptoms of paralysis in hind limbs were observed after feeding it to rodents. The susceptibility to this rodenticide in Rattus rattus increased with the increase in its concentration. Experimental observations revealed that RH-787 bait with 0.0125% concentration affects the reproductive biology of the rats. Bait with 0.025% Vacor proved sublethal and within 5 days 70% mortality was observed, while 100% mortality was observed when rats were fed with 0.05% Vacor