Search

Scholarly Works (1 results)

Article
Peer Reviewed

Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice

Szoka, Francis;
Sockolosky, JT;
Kivimäe, S;
Szoka, FC

UC San Francisco Previously Published Works (2014)

We explore a strategy to substantially increase the half-life of recombinant proteins by genetic fusion to FcIII, a 13-mer IgG-Fc domain binding peptide (IgGBP) originally identified by DeLano and co-workers at Genentech [DeLano WL, et al. (2000) Science 2