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Scholarly Works (1 results)

Article
Peer Reviewed

A Positive Feedback Loop Links Opposing Functions of P-TEFb/Cdk9 and Histone H2B Ubiquitylation to Regulate Transcript Elongation in Fission Yeast

Shokat, Kevan;
Sansó, M;
Lee, KM;
Viladevall, L;
Jacques, PE;
Pagé, V;
Nagy, S;
Racine, A;
St, CV;
Zhang, C;
Shokat, KM

UC San Francisco Previously Published Works (2012)

Transcript elongation by RNA polymerase II (RNAPII) is accompanied by conserved patterns of histone modification. Whereas histone modifications have established roles in transcription initiation, their functions during elongation are not understood. Mono-u