Climate change is exacerbating drought and water stress in several global regions, including some parts of the United States. During times of drought in the U.S., municipal governments, private water suppliers and non-profits commonly deploy advocacy campaigns and incentive programs targeting reductions in residential water use through actions including: repairing leaks, shutting off taps, and installing new water-saving appliances. We asked whether these campaigns have the potential to alleviate water stress during drought at the county scale by estimating the potential impact of full adoption of such actions. In 2010, we show that the maximum potential use reductions from these residential actions may only alleviate water stress in 6% (174) of U.S. counties. The potential impact of domestic programs is limited by the relative dominance of agriculture water withdrawal, the primary water user in 50% of U.S. counties. While residential actions do achieve some water demand savings, they are not sufficient to alter water stress in the majority of the continental U.S. We recommend redirecting advocacy efforts and incentives to individual behaviors that can influence agricultural water use.