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Scholarly Works (1 results)

Article
Peer Reviewed

Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells

Jablons, David;
You, B;
Yang, YL;
Xu, Z;
Dai, Y;
Liu, S;
Mao, JH;
Tetsu, O;
Li, H;
Jablons, DM;
You, L

UC San Francisco Previously Published Works (2015)

Alterations of the EGFR/ERK and Hippo/YAP pathway have been found in nonsmall cell lung cancer (NSCLC). Herein, we show that ERK1 and ERK2 have an effect on the Hippo/YAP pathway in human NSCLC cells. Firstly, inhibition of ERK1/2 by siRNA or small-molecul