This chapter examines changes in telecommuting and the resulting activity-travel behavior during the COVID-19 pandemic, with a particular focus on California. A geographical approach was taken to “zoom in” to the county level and to major regions in California and to “zoom out” to comparable states (New York, Texas, Florida). Nearly one-third of the domestic workforce worked from home during the pandemic, a rate almost six times higher than the pre-pandemic level. At least one member from 35% of U.S. households replaced in-person work with telework; these individuals tended to belong to higher income, White, and Asian households. Workplace visits have continued to remain below pre-pandemic levels, but visits to non-work locations initially declined but gradually increased over the first nine months of the pandemic. During this period, the total number of trips in all distance categories except long-distance travel decreased considerably. Among the selected states, California experienced a higher reduction in both work and non-workplace visits and the State’s urban counties had higher reductions in workplace visits than rural counties. The findings of this study provide insights to improve our understanding of the impact of telecommuting on travel behavior during the pandemic.