© 2016 Diz-Muñoz et al.For efficient polarity and migration, cells need to regulate the magnitude and spatial distribution of actin assembly. This process is coordinated by reciprocal interactions between the actin cytoskeleton and mechanical forces. Actin

© 2015 Nature America, Inc. All rights reserved.A fundamental challenge in treating disease is identifying molecular states that affect cellular responses to drugs. Here, we focus on glycogen synthase kinase 3 (GSK-3), a key regulator for many of the hallm

We provide a detailed description and classification of solutions to the curve shortening equation in Rn that are invariant under one-parameter symmetry groups of the equation. We pay particular attention to geometric properties of the curves and asymptoti

© 2016 Nature America, Inc. All rights reserved.High-content, image-based screens enable the identification of compounds that induce cellular responses similar to those of known drugs but through different chemical structures or targets. A central challeng