This study is a preliminary evaluation of the potential for using Seawater Source Cooling (SWSC) to air condition commercial buildings in California. It also identifies the regulatory policies and permitting requirements that influence implementation of SWSC projects in California. The technical and economic feasibility of SWSC systems for both individual buildings and district cooling systems is examined, as is the viability of application to existing buildings and to new construction and major retrofits that employ radiant cooling and other advanced cooling technologies that allow the use of higher temperature chilled water. Three case studies are included. Recommendations for further study are presented.