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Scholarly Works (2 results)

Article
Peer Reviewed

Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to fas signaling

Pulliam, D;
Wang, Q;
Na, B;
Ou, JHJ;
Pulliam, L;
Yen, TSB

UC San Francisco Previously Published Works (2012)

Hepatitis B virus (HBV) is a major etiological factor of hepatocellular carcinoma (HCC). However, the precise pathogenetic mechanisms linking HBV infection and HCC remain uncertain. It has been reported that decreased antioxidant enzyme activities are asso

Article
Peer Reviewed

Lipid Droplet-Binding Protein TIP47 Regulates Hepatitis C Virus RNA Replication through Interaction with the Viral NS5A Protein

Greene, Warner;
Ott, Melanie;
Vogt, DA;
Camus, G;
Herker, E;
Webster, BR;
Tsou, CL;
Greene, WC;
Yen, TSB

UC San Francisco Previously Published Works (2013)

The nonstructural protein NS5A has emerged as a new drug target in antiviral therapies for Hepatitis C Virus (HCV) infection. NS5A is critically involved in viral RNA replication that takes place at newly formed membranes within the endoplasmic reticulum (