- Anderson, Emily;
- Choi, Yun;
- Buchsbaum, Rachel J;
- Klein, Andreas;
- Ky, Bonnie;
- Landsburg, Daniel;
- Durani, Urshila;
- Ruddy, Kathryn J;
- Yu, Anthony F;
- Leong, Darryl;
- Asnani, Aarti;
- Neilan, Tomas G;
- Ganatra, Sarju;
- Bloom, Michelle;
- Barac, Ana;
- Yang, Eric H;
- Deswal, Anita;
- Cheng, Richard K;
- Weiss, Matthias;
- Evens, Andrew M;
- Kahl, Brad;
- Friedberg, Jonathan W;
- Parsons, Susan K;
- Upshaw, Jenica N
The optimal treatment of patients with diffuse large B-cell lymphoma (DLBCL) or Hodgkin lymphoma (HL) with preexisting cardiomyopathy is uncertain. An anonymous, electronic survey was distributed by e-mail to three US lymphoma cooperative groups, two community hospitals, and twelve academic medical systems, and distributed at one international lymphoma meeting. Fifty hematology-oncology providers caring for patients with lymphoma were included. In response to a vignette of a 67-yo with Stage III DLBCL with LVEF of 40-45%, 15 (30%) would use non-anthracycline regimens, 13 (26%) R-CHOP with liposomal doxorubicin instead of doxorubicin, 11 (22%) R-CHOP without modification and 6 (12%) R-CHOP with a continuous doxorubicin infusion. In a second vignette of a patient with HL in remission after frontline treatment with doxorubicin cumulative dose 300 mg/m2, 16 (32%) would order an echocardiogram after treatment. There was substantial variability in preferred treatment regimens with preexisting cardiomyopathy and in cardiac monitoring after anthracycline.