Abstract. The climate regime shift during the 1980s had a substantial impact on the terrestrial ecosystems and vegetation at different scales. However, the mechanisms driving vegetation changes, before and after the shift, remain unclear. In this study, we used a biophysical-dynamic vegetation model to estimate large-scale trends in terms of carbon fixation, vegetation growth, and expansion during the period 1958–2007, and to attribute these changes to environmental drivers including elevated atmospheric CO2 concentration (hereafter eCO2), global warming, and climate variability (hereafter CV). Simulated Leaf Area Index (LAI) and Gross Primary Product (GPP) were evaluated against observation-based data. Significant spatial correlations are found (correlations > 0.87), along with regionally varying temporal correlations of 0.34–0.80 for LAI and 0.45–0.83 for GPP. More than 40 % of the global land area shows significant trends in LAI and GPP since the 1950s: 11.7 % and 19.3 % of land has consistently positive LAI and GPP trends, respectively; while 17.1 % and 20.1 % of land, saw LAI and GPP trends respectively, reverse during the 1980s. Vegetation fraction cover (FRAC) trends, representing vegetation expansion/shrinking, are found at the edges of semi-arid areas and polar areas. Overall, eCO2 consistently contributes to positive LAI and GPP trends in the tropics. Global warming is shown to mostly affected LAI, with positive effects in high latitudes and negative effects in subtropical semi-arid areas. CV is found to dominate the variability of FRAC, LAI, and GPP in the semi-humid and semi-arid areas. The eCO2 and global warming effects increased after the 1980s, while the CV effect reversed during the 1980s. In addition, plant competition is shown to have played an important role in determining which driver dominated the regional trends. This paper presents a new insight into ecosystem variability and changes in the varying climate since the 1950s.