This article reports the author’s recent research in developing a holistic model for various levels of digital library (DL) evaluation in which perceived important criteria from heterogeneous stakeholder groups are organized and presented. To develop such a model, the author applieda three-stage research approach: exploration, confirmation, and verification. During the exploration stage, a literature review was conducted followed by an interview, along with a card sorting technique, to collect important criteria perceived by DL experts. Then the criteria identified were used for developing an online survey during the confirmation stage. Survey respondents (431 in total)from 22 countries rated the importance of the criteria. A holistic DL evaluation model was constructed using statistical  techniques. Eventually, the verification stage was devised to test the reliability of the model in the context of searching and evaluating an operational DL. The proposed model fills two lacunae in the DL domain: (a) the lack of a comprehensive and flexible framework to guide and benchmark evaluations,and (b) the uncertainty about what divergence exists among heterogeneous DL stakeholders, including general users.

A new study reveals that a high-sugar diet acutely alters human sperm small RNA profiles after 1 week and that these changes are associated with changes in sperm motility. This rapid response by sperm to nutritional fluctuation raises intriguing questions regarding the underlying mechanisms and the potential effects on offspring metabolic health.

A hereditary system that is based on double-helix DNA sequences provides a stable way to store inherited traits and is favored by most life forms on Earth. However, emerging studies on the phenomenon of non-DNA sequence-based inheritance in multiple species, including mammals, urges a rethinking of the nature of hereditary information carriers and the ways in which they encode heritable traits. In this short opinion piece, we discuss how potential hereditary information carriers such as DNA-associated proteins, epigenetic marks, RNAs and organelles could function via distinct and synergistic modes of action in encoding and transmitting ancestral traits, either inherited or acquired from the environment. In particular, we discuss how the 3D structure of chromatin, in addition to its DNA sequence, may represent a higher-order carrier of hereditary information.

A new study reveals that a high-sugar diet acutely alters human sperm small RNA profiles after 1 week and that these changes are associated with changes in sperm motility. This rapid response by sperm to nutritional fluctuation raises intriguing questions regarding the underlying mechanisms and the potential effects on offspring metabolic health.

Background

Syndromic surveillance has been widely adopted as a real-time monitoring tool for timely response to disease outbreaks. During the second wave of the pH1N1 pandemic in Fall 2009, two major universities in Washington, DC collected data that were potentially indicative of influenza-like illness (ILI) cases in students and staff. In this study, our objectives were three-fold. The primary goal of this study was to characterize the impact of pH1N1 on the campuses as clearly as possible given the data available and their likely biases. In addition, we sought to evaluate the strengths and weaknesses of the data series themselves, in order to inform these two universities and other institutions of higher education (IHEs) about real-time surveillance systems that are likely to provide the most utility in future outbreaks (at least to the extent that it is possible to generalize from this analysis).

Methods

We collected a wide variety of data that covered both student ILI cases reported to medical and non-medical staff, employee absenteeism, and hygiene supply distribution records (from University A only). Communication data were retrieved from university broadcasts, university preparedness websites, and H1N1-related on campus media reports. Regional data based on the Centers for Disease Control and Prevention Outpatient Influenza-like Illness Surveillance Network (CDC ILINet) surveillance network, American College Health Association (ACHA) pandemic influenza surveillance data, and local Google Flu Trends were used as external data sets. We employed a "triangulation" approach for data analysis in which multiple contemporary data sources are compared to identify time patterns that are likely to reflect biases as well as those that are more likely to be indicative of actual infection rates.

Results

Medical personnel observed an early peak at both universities immediately after school began in early September and a second peak in early November; only the second peak corresponded to patterns in the community at large. Self-reported illness to university deans' offices was also relatively increased during mid-term exam weeks. The overall volume of pH1N1-related communication messages similarly peaked twice, corresponding to the two peaks of student ILI cases.

Conclusions

During the 2009 H1N1 pandemic, both University A and B experienced a peak number of ILI cases at the beginning of the Fall term. This pattern, seen in surveillance systems at these universities and to a lesser extent in data from other IHEs, most likely resulted from students bringing the virus back to campus from their home states coupled with a sudden increase in population density in dormitories and lecture halls. Through comparison of data from different syndromic surveillance data streams, paying attention to the likely biases in each over time, we have determined, at least in the case of the pH1N1 pandemic, that student health center data more accurately depicted disease transmission on campus at both universities during the Fall 2009 pandemic than other available data sources.

Purpose – Digital humanities (DH) has become a much discussed topic among both humanities scholars and library professionals. The library and information science (LIS) community has taken efforts in providing new facilities and developing new services to meet humanities scholars’ changing research behaviors and needs employing digital tools and methods. How to effectively collaborate with the DH community has been a challenging task to LIS in their digital library (DL) development endeavors. The purpose of this paper is to discover productive ways for LIS to support DH scholarship, specifically, what DL components, including content, technology, and service, should and could be developed for digital humanists. Design/methodology/approach – As an initial effort of the Digital Humanities Interest Group at University of California, Irvine Libraries, the examination is primarily based on a cross-boundary environmental scan in both DH and DL fields. The environmental survey includes both a literature review and web and physical site visits. The survey results, especially a gap analysis between the behaviors and needs of humanities scholars and the digital content, technologies, and services currently offered by the DL community, are used to shape the proposed roles of DH librarianship. Findings – First, DH’s innovative approach to research and teaching practices brings opportunities and challenges. Second, DH research is collaborative work. Third, major channels are established for the DH community. Fourth, various tools and data sets are developed to support different types of projects. Fifth, DH community has unbalanced geographical and disciplinary distribution. Sixth, DH research output still lacks attention, integration, and sustainability. Finally, LIS professionals play unique roles in DH projects. Overall, the communities of DH and DL share common goals and tasks. Practical implications – This paper proposes these present and future roles of LIS professionals: creator and contributor; curator; messenger and liaison; educator; mediator and interpreter; host; partner; innovator; “hybrid scholar”; advocate; consultant. At the organizational level, libraries should demonstrate higher efficiency and effectiveness in the services by revamping organizational culture or structure to stimulate and realize more and deeper cross-boundary conversations and collaborations. On a larger scale, the DL community should strive to become more visible, valuable, and approachable to the DH community; and even better, become part of it. Originality/value – This paper examines both DH and DL fields critically and connects the two communities by discovering gaps and commonalities. Based on the findings, the authors recommend roles and actions to be taken by LIS professionals, libraries, and the DL community. This paper is valuable to both humanities scholars who are seeking support in their research using digital methods and LIS professionals who are interested in providing more effective and suitable services. The paper also helps library administrators and aspiring librarians better understand the concept of DH and grasp insight on the present and future of DH librarianship.