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Bioinorganic Chemistry of Hydrogen Sulfide: Detection, Delivery, and Interactions with Metalloproteins
Abstract
Abstract: Hydrogen sulfide (H2S) has received significant attention in the past two decades for its role in biological processes. Despite numerous studies on the biological activity of this gas, the specific nature of the interaction between H2S and metalloproteins and biologically relevant metal ions remains largely unknown. The current understanding of the chemical biology of H2S with metalloproteins and enzymes is discussed herein. The utility of inorganic complexes as tools for the detection and delivery of H2S under biologically relevant conditions is also discussed.
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