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Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells.

  • Author(s): Ashworth, Alan
  • Bajrami, I
  • Kigozi, A
  • Van, A
  • Brough, R
  • Frankum, J
  • Lord, CJ
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3491838?pdf=render
No data is associated with this publication.
Abstract

PARP inhibitors have been proposed as a potential targeted therapy for patients with triple-negative (ER-, PR-, HER2-negative) breast cancers. However, it is as yet unclear as to whether single agent or combination therapy using PARP inhibitors would be mo

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