Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells.
- Author(s): Ashworth, Alan
- Bajrami, I
- Kigozi, A
- Van, A
- Brough, R
- Frankum, J
- Lord, CJ
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3491838?pdf=render
PARP inhibitors have been proposed as a potential targeted therapy for patients with triple-negative (ER-, PR-, HER2-negative) breast cancers. However, it is as yet unclear as to whether single agent or combination therapy using PARP inhibitors would be mo
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