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Open Access Publications from the University of California

Human placental and intestinal alkaline phosphatase genes map to 2q34-q37.

  • Author(s): Griffin, CA
  • Smith, M
  • Henthorn, PS
  • Harris, H
  • Weiss, MJ
  • Raducha, M
  • Emanuel, BS
  • et al.
Creative Commons 'BY' version 4.0 license

The alkaline phosphatases comprise a multigene enzyme family that hydolyze phosphate esters and are widely distributed in nature. Three main classes have been isolated from humans, the placental, intestinal, and liver/bone/kidney forms. We have mapped the placental and intestinal alkaline phosphatase genes to 2q34-q37 by using chromosomal in situ hybridization and a somatic-cell hybrid panel.

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