Improving drug discovery with high-content phenotypic screens by systematic selection of reporter cell lines
- Author(s): Altschuler, Steven
- Kang, J
- Hsu, CH
- Wu, Q
- Liu, S
- Coster, AD
- Posner, BA
- Altschuler, SJ
- Wu, LF
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4844861?pdf=render
© 2016 Nature America, Inc. All rights reserved.High-content, image-based screens enable the identification of compounds that induce cellular responses similar to those of known drugs but through different chemical structures or targets. A central challeng
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