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Molecular Imaging of Metabolic Reprograming in Mutant IDH Cells.

  • Author(s): Ronen, Sabrina
  • Viswanath, P
  • Chaumeil, MM
  • Ronen, SM
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4789800?pdf=render
No data is associated with this publication.
Abstract

Mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) have recently been identified as drivers in the development of several tumor types. Most notably, cytosolic IDH1 is mutated in 70-90% of low-grade gliomas and upgraded glioblastomas, and mito

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