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Diabetic β Cells: To Be or Not To Be?
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https://doi.org/10.1016/j.cell.2012.08.021Abstract
β cell dysfunction with subsequent apoptosis is considered a significant contributor to the development of type 2 diabetes. Emerging data from Talchai et al. suggest β cell dedifferentiation as an alternative mechanism of insulin insufficiency that might be more amenable to intervention in at least a subset of patients.
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