Skip to main content
Open Access Publications from the University of California

Approximate Variance-Stabilizing Transformations for Gene-Expression Microarray Data


Motivation: A variance stabilizing transformation for microarray data was recently introduced independently by several research groups. This transformation has sometimes been called the generalized logarithm or glog transformation. In this paper, we derive several alternative approximate variance stabilizing transformations that may be easier to use in some applications. Results: We demonstrate that the started-log and the loglinear- hybrid transformation families can produce approximate variance stabilizing transformations for microarray data that are nearly as good as the generalized logarithm (glog) transformation. These transformations may be more convenient in some applications.

Main Content
For improved accessibility of PDF content, download the file to your device.
Current View