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Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation.

  • Author(s): Taunton, Jack
  • Lakkaraju, AKK
  • Thankappan, R
  • Mary, C
  • Garrison, JL
  • Strub, K
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3395660?pdf=render
No data is associated with this publication.
Abstract

Mammalian cells secrete a large number of small proteins, but their mode of translocation into the endoplasmic reticulum is not fully understood. Cotranslational translocation was expected to be inefficient due to the small time window for signal sequence

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