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Probing antibody internal dynamics with fluorescence anisotropy and molecular dynamics simulations

  • Author(s): Dill, Ken
  • Kortkhonjia, E
  • Brandman, R
  • Zhou, JZ
  • Voelz, VA
  • Chorny, I
  • Kabakoff, B
  • Patapoff, TW
  • Dill, KA
  • Swartz, TE
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3893241?pdf=render
No data is associated with this publication.
Abstract

The solution dynamics of antibodies are critical to antibody function. We explore the internal solution dynamics of antibody molecules through the combination of time-resolved fluorescence anisotropy experiments on IgG1 with more than two microseconds of a

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