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Estimation of malaria haplotype and genotype frequencies: A statistical approach to overcome the challenge associated with multiclonal infections

Published Web Location

http://europepmc.org/articles/PMC4004158?pdf=render
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Abstract

Background: Reliable measures of anti-malarial resistance are crucial for malaria control. Resistance is typically a complex trait: multiple mutations in a single parasite (a haplotype or genotype) are necessary for elaboration of the resistant phenotype.

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