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Estimation of malaria haplotype and genotype frequencies: A statistical approach to overcome the challenge associated with multiclonal infections

  • Author(s): Rosenthal, Philip
  • Taylor, AR
  • Flegg, JA
  • Nsobya, SL
  • Yeka, A
  • Kamya, MR
  • Rosenthal, PJ
  • Dorsey, G
  • Sibley, CH
  • Guerin, PJ
  • Holmes, CC
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4004158?pdf=render
No data is associated with this publication.
Abstract

Background: Reliable measures of anti-malarial resistance are crucial for malaria control. Resistance is typically a complex trait: multiple mutations in a single parasite (a haplotype or genotype) are necessary for elaboration of the resistant phenotype.

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