New insights about enzyme evolution from large scale studies of sequence and structure relationships
- Author(s): Babbitt, Patricia
- Brown, SD
- Babbitt, PC
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4215206?pdf=render
© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.Understanding how enzymes have evolved offers clues about their structure-function relationships and mechanisms. Here, we describe evolution of functionally diverse enzyme superfami