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TBX5 and NuRD Divide the Heart
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https://doi.org/10.1016/j.devcel.2016.01.015Abstract
In this issue of Developmental Cell, Waldron et al. (2016) identify an interaction between a master regulator of heart development, TBX5, and the NuRD complex and describe how mutations affecting the interaction may contribute to congenital heart disease. Furthermore, these interactions may have contributed to the evolution of cardiac septation.
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