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Open Access Publications from the University of California

NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis

  • Author(s): Arron, Sarah
  • South, AP
  • Purdie, KJ
  • Watt, SA
  • Haldenby, S
  • Den, NY
  • Dimon, MT
  • Arron, ST
  • Kluk, MJ
  • Aster, JC
  • McHugh, A
  • et al.

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Cutaneous SCC (cSCC) is the most frequently occuring skin cancer with metastatic potential and can manifest rapidly as a common side effect in patients receiving systemic kinase inhibitors. Here, we use massively parallel exome and targeted level sequencin

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