The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling.
- Author(s): Ashworth, Alan
- Rajan, N
- Elliott, RJR
- Smith, A
- Sinclair, N
- Swift, S
- Lord, CJ
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC4322962?pdf=render
CYLD, an ubiquitin hydrolase, has an expanding repertoire of regulatory roles in cell signalling and is dysregulated in a number of cancers. To dissect CYLD function we used a proteomics approach to identify CYLD interacting proteins and identified MIB2, a
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