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Open Access Publications from the University of California

Functional diffuse optical spectroscopy of human breast tissue

  • Author(s): Tromberg, BJ
  • Cerussi, AE
  • Jakubowski, D
  • Shah, N
  • Bevilacqua, F
  • Berger, AJ
  • Butler, J
  • Holcombe, RF
  • et al.

A method was described for using steady-state and frequency-domain reflectance measurements to obtain broad wavelength quantitative data with deep tissue penetration. Fundamental information on tissue biochemistry and structure was provided using the wavelength-dependence of absorption and scattering parameters. Results showed that total hemoglobin content, water and lipid percentage can be measured using this technique.

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