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Protective role of STING against gliomagenesis: Rational use of STING agonist in anti-glioma immunotherapy
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https://doi.org/10.1080/2162402x.2014.999523Abstract
We recently reported that STING contributes to antiglioma immunity by triggering type I IFN induction in glioma microenvironment. Moreover, intratumoral administration of STING agonist improved the efficacy of peptide vaccination in a mouse glioma model, suggesting the rational use of STING agonists in the immunotherapy of brain tumor.
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