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The Path from Pluripotency to Skeletal Muscle: Developmental Myogenesis Guides the Way

Published Web Location

https://doi.org/10.1016/j.stem.2015.08.017
Abstract

Following cues from mouse embryogenesis, Chal et al. (2015) identified key regulators of skeletal myogenesis from mouse and human pluripotent stem cells. Emerging myogenic progenitors were specified to form multinucleated fibers that enabled development of quiescent, satellite cell-like progenitors and a model for Duchenne Muscular Dystrophy.

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