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Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses

Published Web Location

http://europepmc.org/articles/PMC4886361?pdf=render
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Abstract

© 2016 Bannard et al.Antibody affinity maturation occurs in germinal centers (GCs) through iterative rounds of somatic hypermutation and selection. Selection involves B cells competing for T cell help based on the amount of antigen they capture and present

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