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Ubiquitin-mediated fluctuations in MHC class II facilitate efficient germinal center B cell responses

  • Author(s): Shin, Jeoung-Sook
  • Bannard, O
  • McGowan, SJ
  • Ersching, J
  • Ishido, S
  • Victora, GD
  • Shin, JS
  • Cyster, JG
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4886361?pdf=render
No data is associated with this publication.
Abstract

© 2016 Bannard et al.Antibody affinity maturation occurs in germinal centers (GCs) through iterative rounds of somatic hypermutation and selection. Selection involves B cells competing for T cell help based on the amount of antigen they capture and present

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