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Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic

  • Author(s): Shokat, Kevan
  • Walter, Peter
  • Mendez, AS
  • Alfaro, J
  • Morales-Soto, MA
  • Dar, AC
  • McCullagh, E
  • Gotthardt, K
  • Li, H
  • Acosta-Alvear, D
  • Sidrauski, C
  • Korennykh, AV
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4436593?pdf=render
No data is associated with this publication.
Abstract

© 2015, eLife Sciences Publications Ltd. All rights reserved.Two ER membrane-resident transmembrane kinases, IRE1 and PERK, function as stress sensors in the unfolded protein response. IRE1 also has an endoribonuclease activity, which initiates a non-conve

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