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Open Access Publications from the University of California

Widespread inflammatory response to osteoblastoma: The flare phenomenon

  • Author(s): Crim, JR
  • Mirra, JM
  • Eckardt, JJ
  • Seeger, LL
  • et al.

A case of vertebral osteoblastoma caused a diffuse, reactive inflammatory infiltrate in two vertebrae, adjacent ribs, and the paraspinous soft tissues. The authors call this the flare phenomenon. On magnetic resonance images the diffuse inflammatory response caused a misleading appearance that simulated a malignant process (lymphoma or Ewing sarcoma). A computed tomographic myelogram was diagnostic.

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