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Antiviral Drug Discovery To Address the COVID-19 Pandemic.

  • Author(s): Richman, Douglas D
  • et al.

Published Web Location

https://www.nature.com/articles/nsmb758
No data is associated with this publication.
Abstract

The magnitude of the morbidity and mortality inflicted upon the global population in less than 1 year has driven the inescapable conclusion that the discovery and development of effective antiviral drugs for COVID-19 are urgent and should be prioritized. The antiviral drug discovery programs that emerged for HIV and hepatitis C virus have enabled technology and expertise to accelerate this process for SARS-CoV-2. The description of candidate lead inhibitors for the viral main protease (Mpro) exemplifies this accelerated approach and reminds us of the needs and opportunities for addressing this pandemic.

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